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Ginkgolide - Wikipedia

https://en.wikipedia.org/wiki/Ginkgolide

Ginkgolides are biologically active terpenic lactones present in Ginkgo biloba. They are diterpenoids with 20-carbon skeletons.

Total Synthesis of Ginkgolide C and Formal Synthesis ... - ChemRxiv

https://chemrxiv.org/engage/chemrxiv/article-details/62ea69cd3276f05494590bd8

Ginkgolides are diterpenes isolated from ginkgo biloba that exhibit strong PAF antagonistic activity as well as other interesting neuroprotective properties.

CHEBI:136909 - ginkgolide - EMBL-EBI

https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:136909

Ginkgolides, the main active constituents of Ginkgo biloba, possess significant selectively inhibition on platelet-activating factor and ...

Ginkgolides

https://www.drugfuture.com/chemdata/ginkgolides.html

Ginkgolides are sol in acetone, ethanol, methanol, ethyl acetate, THF, dioxane, acetic acid, trifluoroacetic acid, acetonitrile, pyridine, DMSO; sparingly sol ...

Variation of ginkgolides and bilobalide contents in leaves and cell ...

https://link.springer.com/article/10.1007/BF02949319

Ginkgolides (GK) and bilobalide are valuable compounds that belong to the lactone terpene. The contents of these metabolites were determined by HPLC from female ...

Synthesis of the spirotetracyclic core of the ginkgolides via a malonyl ...

https://chemrxiv.org/engage/chemrxiv/article-details/678a839681d2151a0289bd1b

The ginkgolides are a family of terpene trilactone natural products exclusive to the Ginkgo biloba tree. Here, we present a concise ...

Radical Scavenging Potential of Ginkgolides and Bilobalide - MDPI

https://www.mdpi.com/2076-3921/12/2/525

Ginkgolides and bilobalide are hydrophobic compounds sparingly soluble in water [19]. Their chemical features account for their affinity to cell ...

Ginkgolides and Bilobalide: Their Physical, Chromatographic and ...

https://www.researchgate.net/publication/7751253_Ginkgolides_and_Bilobalide_Their_Physical_Chromatographic_and_Spectroscopic_Properties

Ginkgolides are mainly involved the inhibition of platelet-activating factors and atherosclerosis, while bilobalide has been confirmed to have a neuro ...

Ginkgolides and Neuroprotective Effects - SpringerLink

https://link.springer.com/rwe/10.1007/978-3-642-22144-6_146

Its clinical application gained popularity in herbal medicine due to treatment of early-stage Alzheimer's disease, cerebrovascular disorders, ...

Diterpene ginkgolides protect against cerebral ischemia/reperfusion ...

https://www.nature.com/articles/aps2017149

Diterpene ginkgolides meglumine injection (DGMI) is a therapeutic extract of Ginkgo biloba L, which has been used for the treatment of ...

Ginkgolide - an overview | ScienceDirect Topics

https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/ginkgolide

Ginkgolide is a compound extracted from the gymnosperm of Ginkgo biloba, which belongs to diterpene lactone. It is mainly divided into ginkgolides A, B, C, J, K ...

Ginkgolides - Journal of the Chemical Society C - RSC Publishing

https://pubs.rsc.org/en/content/articlelanding/1967/j3/j39670002201

Three bitter principles, ginkgolides A, B, and C, were isolated from the leaves of Ginkgo biloba L. Since the structure of ginkgolide A was established by ...

Chemical structure of the ginkgolides. - ResearchGate

https://www.researchgate.net/figure/Chemical-structure-of-the-ginkgolides_fig2_46125337

Results: GBE, a commonly used dietary supplement, has been shown to act as an antioxidant and freeradical scavenger, a membrane stabilizer, an inhibitor of the ...

Biosynthesis pathways of ginkgolides - PMC

https://pmc.ncbi.nlm.nih.gov/articles/PMC3731879/

This review focuses on the biosynthetic pathways of ginkgolides, the enzymes related to the biosynthesis of the ginkgolides, the genes encoding the enzymes ...

Role of Ginkgolides in the Inflammatory Immune Response of ...

https://www.frontiersin.org/journals/systems-neuroscience/articles/10.3389/fnsys.2020.00045/full

Ginkgolides are one of the important medicinal ingredients in Ginkgo biloba. Many studies have verified that ginkgolides have anti-platelet- ...

Determination of ginkgolides and bilobalide in Ginkgo biloba leaves ...

https://research.wur.nl/en/publications/determination-of-ginkgolides-and-bilobalide-in-ginkgo-biloba-leav

Determination of ginkgolides and bilobalide in Ginkgo biloba leaves and phytopharmaceuticals. T.A. van Beek, H.A. Scheeren, T. Rantio, W.Ch. Melger, G.P. ...

Total Synthesis of Ginkgolide C and Formal Syntheses of ...

https://pubs.acs.org/doi/10.1021/jacs.2c08351

Ginkgolides are diterpenes isolated from Ginkgo biloba that exhibit strong anti-inflammatory and neuroprotective properties.

Neuroregulatory role of ginkgolides - PMC - PubMed Central

https://pmc.ncbi.nlm.nih.gov/articles/PMC8338821/

Ginkgolides are responsible for neuroprotection. Ginkgolides reduce apoptosis in rat brain tissue cells with acute cerebral infarction, thus protecting the ...

Ginkgolide - an overview | ScienceDirect Topics

https://www.sciencedirect.com/topics/neuroscience/ginkgolide

The ginkgolides are a unique class of diterpenoids isolated from the 'fossil' tree Ginkgo biloba L. This tree is the only remaining species of the Ginkgoales.

Ingredient: Ginkgolides - Caring Sunshine

https://caringsunshine.com/ingredients/ingredient-ginkgolides/?srsltid=AfmBOooIq9V0CrsegPcqny3YBp5l6qNWX06D7uS8Hz84_PAdph6Yx0dB

Ginkgolides are a group of biologically active compounds found exclusively in the leaves of the Ginkgo biloba tree, which has a long history of use in ...